Can you "inject marijuanas," as the satirical memes suggest? Yes, but it’s a really, really stupid thing to do, according to a new study. The latest trend in CBD consumption comes in the form of CBD injections. Read on to discover why this could be beneficial to you if you are a CBD enthusiast. Cannabis is widely used recreationally and for symptomatic relief in a number of ailments. However, cannabis has been implicated as a risk factor for the development of psychotic illness. For forty years researchers have utilised intravenous preparations of Δ(9)-THC, as well as several other phytoca …
Can You Inject CBD Oil
Can you “inject marijuanas,” as the satirical memes suggest? Yes, but it’s a really, really stupid thing to do, according to a new study.
A new study found that injecting pure THC triggered schizophrenia-like behaviors in subjects. But, uh, does anyone actually consume weed this way?
The study, conducted by schizophrenia researchers at the Veterans Affairs Healthcare System in Connecticut, and recently published in Neuropsychopharmacology, involved shooting up 22 healthy individuals with 2.5mg THC, 5mg THC, or a placebo (0mg THC). The subjects had previously been “exposed” to cannabis, but none had been diagnosed with cannabis use disorder.
After three separate days of mainlining pure THC, the subjects reported experiencing schizophrenia-like symptoms, increased anxiety, altered perceptions, euphoria, and a host of memory and speech issues. Their blood also showed increased levels of cortisol, the primary stress hormone. Not surprisingly, the researchers concluded that THC produces psychotic behaviors, and more studies are needed to see how cannabinoid receptors may contribute to psychotic disorders.
Usually when we see anything about injecting THC or “marijuanas,” it comes from satirical social media accounts that claim shooting up weed can cause everything from suddenly turning someone gay to spontaneous death (again, these are memes). But intravenous administration of THC is a standard (though not terribly common) practice in cannabis studies, since it gives researchers precise control over dosing. The only problem with this study and others like it is that no one actually injects pure THC. There’s a reason why most consumers prefer to smoke or vape cannabis, after all.
When someone smokes, let’s say, a one-gram joint rolled with weed containing 25 percent THC, that joint contains, roughly, 250mg of THCA, the form of THC that doesn’t get anyone high. Heat converts some THCA into THC — the stuff that gets people lit — but only some THCA turns into the psychoactive form. The average time that heat is applied to the joint isn’t long enough to convert all of the THCA to THC. Furthermore, a bunch of converted THC gets lost in the smoke that wafts from the joint, and even more THC gets stuck in the ash.
So, by the end of it, even if just one person smoked that entire 1-gram joint to the face, they’re only getting a small fraction of that potential 250mg THC, not to mention a cornucopia of other compounds such as other cannabinoids, terpenes, flavonoids, and polyphenols — which all may interact with our brain’s cannabinoid receptors, dulling the negative effects of THC.
In other words, shooting someone up with 2.5mg or 5mg pure THC is kind of a lot, especially for non-stoners, which this study focused on.
In addition to there being next-to-no people who shoot up THC distillate or diamonds on a regular basis, no one shoots up actual weed, either. Back in the ‘70s and ‘80s, some idiots tried that, and they developed what’s called “intravenously injected marijuana disorder.” Basically, folks would boil weed buds into a “broth,” pull that filtered broth up into a syringe, then inject it. Rather than getting lit, they got sick AF instead, which included bouts of vomiting, intense muscle pains, and serious heart problems.
Here’s the thing about IV marijuana disorder, too: There are practically no new case studies on it after 1986, suggesting that only a handful of people did it back in the day. Why? Obviously, it sucks, and it’s potentially life-threatening. Which is why, today and in the past, folks have stuck to puffing their pot.
Does this mean that everything about the VA study is bogus? Not entirely. We know that the endocannabinoid system plays a role in some mental disorders, and cannabis use can aggravate some psychotic symptoms in people particularly prone to them. However, many cannabis patients consume weed to alleviate symptoms of their personality or mood disorders, too, so the issue isn’t black-and-white, nor is it clear-cut.
Oh, and in case if you’re wondering if you can snort weed, yeah, technically, that’s possible. But you’ll end up blowing pot-snot all day and never catching a buzz.
The doctor will CBD you now: Could CBD injections be the future?
Chances are, you’ve heard the initials CBD bandied around over the last few years and you may even have dabbled in CBD usage yourself, so popular is the ingredient in oil form. A few drops under the tongue for a better mood, you say? surely that’s worth a try. It’s hailed as a phenomenon for consumers seeking a healthier lifestyle with a strong desire to address anxiety and stress (two emotions that appear to underpin modern society).
Since the birth of this wellness trend, circa 2018, CBD (cannabidiol) has featured in countless health, beauty and food products, but, like many consumer-led products, due diligence should be carried out before investment to ensure you’re benefiting from the real deal.
But how much do you really know about CBD and what is the best way to benefit from it? We spoke to IVNT (intravenous nutrient therapy) specialist and founder of Vitamin Injections London, Bianca Estelle, to hear all about the launch of London’s first ever CBD injection and how this compares to its product predecessors.
An introduction to CBD
Cannabidiol is an active ingredient derived from the hemp plant, a cousin of the marijuana plant
CBD stands for cannabidiol and is an active ingredient derived from the hemp plant, a cousin of the marijuana (cannabis) plant. Unlike THC, which is also found in marijuana, CBD doesn’t cause intoxication or a high and is therefore safe for use. In fact, there has been evidence to show that it can treat the symptoms of epilepsy but in recent times, its more widely adopted for its general health and wellness benefits.
What are the benefits?
Whilst research is still in its infancy, CBD products are endorsed by many to aid pain, alleviate stress and anxiety, promote healthy sleep patterns and more.
It’s worth noting that the benefits of CBD were first discovered by doctors in the US (where cannabis is legal) with feedback from patients stating that CBD was helping with their anxiety.
How should we take it?
Currently the most popular way of taking CBD is with an oil or tincture applied under the tongue
Here’s the caveat – not all CBD products are created equal and, as we know, marketing guidelines can be somewhat lax, so it’s difficult to separate the wheat from the chaff. As a rough guide, experts say that for most adults, 10mg is fine to start and we needn’t worry about overdosing as scientists are confident that, even at excess, CBD use isn’t dangerous (just be sure to tell your doctor in case it interferes with existing medication). For added reassurance, the World Health Organisation states: ‘In humans, CBD exhibits no effects indicative of any abuse or dependence potential… To date, there is no evidence of public health related problems associated with the use of pure CBD.’ This goes for dosages up to 5000mg a day and to put this into context, some of the products commonly found on the UK market today start at just 1mg.
By far, the most popular way to take CBD is with an oil or tincture, applied under the tongue, but, if we look at the best way to ensure that active ingredients (including vitamins) reach the bloodstream, there may be a better way. Enter Vitamin Injections London and its new CBD injection. Based in London’s affluent Marylebone, the clinic specialises in offering vitamin nutrient therapy, to promote health and wellbeing from the inside out.
Bianca Estelle, founder of Vitamin Injections London
All injections at the clinic bypass the digestive system to deliver active ingredients directly into the bloodstream and the new CBD injection is no exception – this compound is utilised by our bodies Endocannabinoid System and, when injected, CBD is not lost during the digestion process. As such, the maximum amount of the CBD compound is absorbed, ensuring better efficacy and health benefits.
In a nutshell, CBD delivery via injection offers higher concentrations, compared to other alternatives. Company founder Bianca Estelle explains: “Having followed and acutely analysed the popularity of CBD over the last few years, I am thrilled to be able to apply my knowledge and experience to offer the first and only CBD injection here in London. Many clients will benefit from the properties of CBD in a highly concentrated, injectable format and the research and development that we have taken to launch this has been worth the wait.”
Vitamin Injections London’s CBD injections at are available intramuscularly from £200 or intravenously from £350 with course discounts also available.
Cannabis in the arm: what can we learn from intravenous cannabinoid studies?
Cannabis is widely used recreationally and for symptomatic relief in a number of ailments. However, cannabis has been implicated as a risk factor for the development of psychotic illness. For forty years researchers have utilised intravenous preparations of Δ(9)-THC, as well as several other phytocannabinoids, in a laboratory setting. The intravenous route has the most reliable pharmacokinetics, reducing inter-individual variation in bioavailability and is well suited for the delivery of synthetic compounds containing a sole pharmacological moiety. Given the association between cannabinoids and psychotic illness, there has been a resurgence of interest in experimental studies of cannabinoids in humans, and the intravenous route has been employed. Here in a critical review, we appraise the major findings from recent intravenous cannabinoid studies in humans and trace the historical roots of this work back to the 1970’s.
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